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detailed prednisone dosage information for adults and children. The initial dosage of prednisone for adults is 5-60 mg daily. The dosage depends on the medical condition for which this drug is prescribed, the severity of the disease, and the patients response to the treatment. -gradual dose reduction is recommended when doses in excess of physiologic doses (7. 5 mg orally or equivalent) are given for longer than 3 weeks. Main switchboard available 247 to connect you to all departments and services. It comes as an immediate-release tablet, a delayed-release tablet, and a liquid solution. Generally, prednisone treatment begins with a high dose which is gradually reduced over a period of few weeks. The treatment is then stopped or continued as a low-dose therapy, depending on the individual case. The generally recommended, adult and pediatric doses for certain diseases and conditions have been summarized below. Prednisone and prednisolone are used for suppressing the immune system and inflammation. Both drugs are used to treat conditions including arthritis, colitis, asthma, bronchitis, skin problems, and allergies. Learn more about the side effects, dosage, drug interactions and pregnancy safety information. Prednisone is a corticosteroid that comes in oral or liquid form. It works by acting on the immune system to help reduce the inflammation in the airways of people with asthma.