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herpes simplex virus type 1 (hsv-1) is the cause of most cases of herpes esophagitis. Oral herpes is an infection caused by the herpes simplex virus. The virus causes painful sores on your lips, gums, tongue, roof of your mouth, and inside your cheeks. This herpes infection of the throat can be caused by either herpes simplex i or ii although it is more commonly caused by simplex i, commonly called oral herpes. Herpes esophagitis is rare in people with healthy immune systems 8. Herpes outbreaks -- and the spread of this infection into the throat and esophagus -- are more common in people with weakened immune systems 7. Herpes of the throat is more likely to occur in people who have kidney failure, cancer, human immunodeficiency virus (hiv) or aids, in organ transplant recipients, or in people who. Instead, most first cases of herpes affecting the face appear as a sore throat, a sore mouth (which can occasionally ulcerate), swollen neck glands, and a temperature. The classic signs of initial infection in the genital region are a painful, red, ulcerating crop of lesions that can spread over a wide area and may involve the perineum and anus. Although inflammation of the affected site and fluid-filled sores are the most common symptoms of a herpes outbreak, some people may also experience sore throat, fatigue, and headache. There are two types of herpes herpes simplex 1 (hsv1) and herpes simplex 2 (hsv2). hsv-1 is the primary cause of oral herpes but can also lead to genital herpes. Throat herpes is a viral infection of the throat caused by the herpes virus. Herpes simplex 1 and herpes simplex 2 can both be involved in cases of throat herpes. True cases isolated to the throat are relatively rare, but it is not uncommon for people with oral herpes to develop herpes sores in or around the throat in addition to around the lips and on the soft palate. hsv-1 is more commonly associated with herpes in the throat. This virus is the same one that causes cold sores and it is generally transmitted by mouth-to-mouth contact, but can also be passed through oral sex. Hsv-2 is the primary cause of genital herpes, but can also cause oral herpes.